Protherics PLC: Change of Adviser

Protherics Appoints Code Securities As Financial Adviser And Joint Stockbroker And Confirms Panmure Gordon As Joint Stockbroker

The Board of Protherics PLC (the "Company") is pleased to announce the appointment of Code Securities Limited as the Company's financial adviser and joint stockbroker. The Company is also pleased to confirm the appointment of Panmure Gordon, a division of Lazard & Co., Limited, as joint stockbroker. The appointments are effective immediately.

For Further Information Contact:

Protherics PLC
Andrew Heath, Chief Executive		+44 (0)20 7246 9950
Nick Staples, Corporate Affairs
The Maitland Consultancy
Brian Hudspith / Michelle Jeffery		+44 (0)20 7379 5151
Code Securities Limited
Juliet Thompson / Phil Walker		+44 (0)20 7024 2000
Panmure Gordon
Dominic Morley		+44 (0)20 7187 2000

Notes To Editors
Protherics PLC was formed in September 1999 from the merger of Proteus International plc and Therapeutic Antibodies Inc. Protherics is an international biopharmaceutical company, engaged in the development, production and commercialisation of immunopharmaceuticals and cancer therapies.The Company's ordinary shares are listed on the Official List of the UK Listing Authority and are traded on the London Stock Exchange. (PTI.L) An electronic version of this will be available at: http://www.protherics.com

Code Securities Limited ("Code") is a newly formed London-based investment banking firm providing a full range of advisory, fundraising and stockbroking services for companies and investors in the European life sciences and medtech sectors. Code is authorised and regulated by the Financial Services Authority and is a member of the London Stock Exchange.